| What are the surgical options for T1 T2, N0 oral cancer with curative intent? | wide excision with 1 cm margins & supra-omohyoid neck dissection (Level I – III) with reconstruction | BASE/ INTERNAL CAROTID ARTERY INVOLVEMENT T1 T2, N0 CANCER OPTIONS WITH CURATIVE INTENT Initial surgery preferred (wide excision with 1 cm margins & supra-omohyoid neck dissection (Level I – III) with reconstruction OR Radical radiation therapy OPTIONS WITH CURATIVE INTENT Initial surgery: wide excision with 1 cm margins + comprehensive neck dissection and reconstruction OR Chemoradiation OR Neo-adjuvant CT followed by surgery INDICATIONS FOR ADJUVANT RT Close margin, positive node(s), or presence of any two of following: LVI, PNI, high grade INDICATIONS FOR ADJUVANT CT-RT: Metastatic nodes with extracapsular extension, involved margins | 115 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | BASE/ INTERNAL CAROTID ARTERY INVOLVEMENT T1 T2, N0 CANCER OPTIONS WITH CURATIVE INTENT Initial surgery preferred (wide excision with 1 cm margins & supra-omohyoid neck dissection (Level I – III) with reconstruction OR Radical radiation therapy OPTIONS WITH CURATIVE INTENT Initial surgery: wide excision with 1 cm margins + comprehensive neck dissection and reconstruction OR Chemoradiation OR Neo-adjuvant CT followed by surgery INDICATIONS FOR ADJUVANT RT Close margin, positive node(s), or presence of any two of following: LVI, PNI, high grade INDICATIONS FOR ADJUVANT CT-RT: Metastatic nodes | 1 | page=1,block=26 | 0.700 | valid |
| What is a potential benefit of screening for oral premalignant disorders and invasive cancer? | detect OPMD and invasive cancer early and improve outcome | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 353 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 1 | page=1,block=3 | 0.700 | valid |
| What can screening for oral cancer achieve? | detect OPMD and invasive cancer early and improve outcome | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 353 | summary | 0.930 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 1 | page=1,block=3 | 0.700 | valid |
| What does the abbreviation FNAC stand for? | Fine needle aspiration cytology | Adjuvant radiation The minimum post-operative radiation dose is 60 Gy/ 6 weeks/ 30# or equivalent to the primary and nodal areas using conventional treatment planning, 3DCRT or IMRT Radical radiation 66-70 Gy is delivered using conventional planning / 3DCRT/IMRT through a telecobalt machine or a LINAC at 1.8 to 2 Gy per fraction over 7-8 weeks (or a biologically equivalent dose) with adequate margins all around the lesion and including level I, II and III nodes CBC: Complete blood count CT: Chemotherapy EUA: Examination under anaesthesia FNAC: Fine needle aspiration cytology IMRT: Intensity-modulated radiation therapy LFT: Liver function tests LVI: Lymphovascular invasion MDT: Multidisciplinary team OPMD: Oculopharyngeal muscular dystrophy PNI: Perineural invasion PTA: Pure tone audiometry RFT: Renal function tests RT: Radiotherapy USG: Ultrasound sonography test July/ 2020 | 550 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | Adjuvant radiation The minimum post-operative radiation dose is 60 Gy/ 6 weeks/ 30# or equivalent to the primary and nodal areas using conventional treatment planning, 3DCRT or IMRT Radical radiation 66-70 Gy is delivered using conventional planning / 3DCRT/IMRT through a telecobalt machine or a LINAC at 1.8 to 2 Gy per fraction over 7-8 weeks (or a biologically equivalent dose) with adequate margins all around the lesion and including level I, II and III nodes CBC: Complete blood count CT: Chemotherapy EUA: Examination under anaesthesia FNAC: Fine needle aspiration cytology IMRT: |
| What are some oral premalignant disorders associated with tobacco use? | leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 183 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 1 | page=1,block=3 | 0.700 | valid |
| What are some risk factors for oral cancer? | Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 2 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | • Tobacco • Alcohol • Areca nut • Sharp tooth • Ill-fitting dentures Non healing ulcer/ sore in the mouth especially in a tobacco chewer or smoker Oral premalignant disorders (OPMD): leukoplakia/ erythroplakia/sub mucous fibrosis, lichen planus Neck mass Difficulty in opening mouth Difficulty in protrusion of tongue Pain referred to ear Screening can detect OPMD and invasive cancer early and improve outcome. | 1 | page=1,block=3 | 0.700 | valid |
| What are some techniques used for delivering post-operative or radical radiation? | conventional treatment planning, 3DCRT or IMRT | Adjuvant radiation The minimum post-operative radiation dose is 60 Gy/ 6 weeks/ 30# or equivalent to the primary and nodal areas using conventional treatment planning, 3DCRT or IMRT Radical radiation 66-70 Gy is delivered using conventional planning / 3DCRT/IMRT through a telecobalt machine or a LINAC at 1.8 to 2 Gy per fraction over 7-8 weeks (or a biologically equivalent dose) with adequate margins all around the lesion and including level I, II and III nodes CBC: Complete blood count CT: Chemotherapy EUA: Examination under anaesthesia FNAC: Fine needle aspiration cytology IMRT: Intensity-modulated radiation therapy LFT: Liver function tests LVI: Lymphovascular invasion MDT: Multidisciplinary team OPMD: Oculopharyngeal muscular dystrophy PNI: Perineural invasion PTA: Pure tone audiometry RFT: Renal function tests RT: Radiotherapy USG: Ultrasound sonography test July/ 2020 | 135 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | Adjuvant radiation The minimum post-operative radiation dose is 60 Gy/ 6 weeks/ 30# or equivalent to the primary and nodal areas using conventional treatment planning, 3DCRT or IMRT Radical radiation 66-70 Gy is delivered using conventional planning / 3DCRT/IMRT through a telecobalt machine or a LINAC at 1.8 to 2 Gy per fraction over 7-8 weeks (or a biologically equivalent dose) with adequate margins all around the lesion and including level I, II and III nodes CBC: Complete blood count CT: Chemotherapy EUA: Examination under anaesthesia FNAC: Fine needle aspiration cytology IMRT: |
| What are the indications for adjuvant radiation therapy in oral cancer treatment? | Close margin, positive node(s), or presence of any two of following: LVI, PNI, high grade | BASE/ INTERNAL CAROTID ARTERY INVOLVEMENT T1 T2, N0 CANCER OPTIONS WITH CURATIVE INTENT Initial surgery preferred (wide excision with 1 cm margins & supra-omohyoid neck dissection (Level I – III) with reconstruction OR Radical radiation therapy OPTIONS WITH CURATIVE INTENT Initial surgery: wide excision with 1 cm margins + comprehensive neck dissection and reconstruction OR Chemoradiation OR Neo-adjuvant CT followed by surgery INDICATIONS FOR ADJUVANT RT Close margin, positive node(s), or presence of any two of following: LVI, PNI, high grade INDICATIONS FOR ADJUVANT CT-RT: Metastatic nodes with extracapsular extension, involved margins | 459 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | BASE/ INTERNAL CAROTID ARTERY INVOLVEMENT T1 T2, N0 CANCER OPTIONS WITH CURATIVE INTENT Initial surgery preferred (wide excision with 1 cm margins & supra-omohyoid neck dissection (Level I – III) with reconstruction OR Radical radiation therapy OPTIONS WITH CURATIVE INTENT Initial surgery: wide excision with 1 cm margins + comprehensive neck dissection and reconstruction OR Chemoradiation OR Neo-adjuvant CT followed by surgery INDICATIONS FOR ADJUVANT RT Close margin, positive node(s), or presence of any two of following: LVI, PNI, high grade INDICATIONS FOR ADJUVANT CT-RT: Metastatic nodes |
| What assessments are conducted to evaluate the impact of oral cancer on communication and nutrition? | Pure tone audiometry (PTA) • Speech and swallowing assessment | Treatment of oral cancer is ideally delivered by a multidisciplinary team(MDT) • Clinical examination, +/- examination under anaesthesia (EUA), assess pain, nutritional status, & oro-dental hygiene • USG neck / CT scan head & neck • Evaluate upper aerodigestive tract for second primary • Biopsy from primary site, FNAC from neck node • CBC, LFT, RFT, blood sugar, chest X-ray, ECG • Tobacco cessation for patient and care givers • Pure tone audiometry (PTA) • Speech and swallowing assessment • Define clinical and radiological staging, goals of treatment | 432 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | Treatment of oral cancer is ideally delivered by a multidisciplinary team(MDT) • Clinical examination, +/- examination under anaesthesia (EUA), assess pain, nutritional status, & oro-dental hygiene • USG neck / CT scan head & neck • Evaluate upper aerodigestive tract for second primary • Biopsy from primary site, FNAC from neck node • CBC, LFT, RFT, blood sugar, chest X-ray, ECG • Tobacco cessation for patient and care givers • Pure tone audiometry (PTA) • Speech and swallowing assessment • Define clinical and radiological staging, goals of treatment |
| What diagnostic procedures are performed to evaluate oral cancer? | Biopsy from primary site, FNAC from neck node | Treatment of oral cancer is ideally delivered by a multidisciplinary team(MDT) • Clinical examination, +/- examination under anaesthesia (EUA), assess pain, nutritional status, & oro-dental hygiene • USG neck / CT scan head & neck • Evaluate upper aerodigestive tract for second primary • Biopsy from primary site, FNAC from neck node • CBC, LFT, RFT, blood sugar, chest X-ray, ECG • Tobacco cessation for patient and care givers • Pure tone audiometry (PTA) • Speech and swallowing assessment • Define clinical and radiological staging, goals of treatment | 289 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1726568903_lip_and_oral_cancer.pdf | Treatment of oral cancer is ideally delivered by a multidisciplinary team(MDT) • Clinical examination, +/- examination under anaesthesia (EUA), assess pain, nutritional status, & oro-dental hygiene • USG neck / CT scan head & neck • Evaluate upper aerodigestive tract for second primary • Biopsy from primary site, FNAC from neck node • CBC, LFT, RFT, blood sugar, chest X-ray, ECG • Tobacco cessation for patient and care givers • Pure tone audiometry (PTA) • Speech and swallowing assessment • Define clinical and radiological staging, goals of treatment |