| What is the purpose of the MGIT system? | Liquid culture medium for mycobacteria | MUSCULOSKELETAL PLEURAL MENINGITIS LYMPHADENITIS UROGENITAL FEMALE GENITAL GASTROINTESTINAL FNA: Fine needle aspirate LJ medium: Lowenstein Jensen medium MGIT: Mycobacteria Growth Indicator tube (Liquid culture medium for mycobacteria) NAAT: Nucleic Acid Amplification Tests-Xpert MTB/RIF/TrueNat PHC: Primary health Centre TB: Tuberculosis IRL: Intermediate Reference laboratory | 196 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | MUSCULOSKELETAL PLEURAL MENINGITIS LYMPHADENITIS UROGENITAL FEMALE GENITAL GASTROINTESTINAL FNA: Fine needle aspirate LJ medium: Lowenstein Jensen medium MGIT: Mycobacteria Growth Indicator tube (Liquid culture medium for mycobacteria) NAAT: Nucleic Acid Amplification Tests-Xpert MTB/RIF/TrueNat PHC: Primary health Centre TB: Tuberculosis IRL: Intermediate Reference laboratory | 25 | page=25,block=26 | 0.700 | valid |
| What does 'USG KUB' stand for? | Ultrasonography Kidney, Ureter and Bladder | USG KUB: Ultrasonography Kidney, Ureter and Bladder RR: Rifampicin Resistant URINE AFB: Urine for Acid-fast Bacillus R: Rifampicin RFT: Renal Function Test NTEP: National Tuberculosis Elimination Programme NAAT: Nucleic Acid Amplification Test MDR: Multi Drug Resistant LUTS: Lower Urinary Tract Symptoms LFT: Liver Function Test IVP: Intravenous Pyelogram HDN: Hydronephrosis HDUN: Hydroureteronephrosis H: Isoniazid ESR: Erythrocyte Sedimentation Rate E: Ethambutol DS-TB: Drug Susceptible Tuberculosis DJS: Double J Stent CXR: Chest X- Ray CBC: Complete Blood Count CT: Computed Tomography ATT: Anti-tubercular treatment | 9 | definition | 0.980 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | USG KUB: Ultrasonography Kidney, Ureter and Bladder RR: Rifampicin Resistant URINE AFB: Urine for Acid-fast Bacillus R: Rifampicin RFT: Renal Function Test NTEP: National Tuberculosis Elimination Programme NAAT: Nucleic Acid Amplification Test MDR: Multi Drug Resistant LUTS: Lower Urinary Tract Symptoms LFT: Liver Function Test IVP: Intravenous Pyelogram HDN: Hydronephrosis HDUN: Hydroureteronephrosis H: Isoniazid ESR: Erythrocyte Sedimentation Rate E: Ethambutol DS-TB: Drug Susceptible Tuberculosis DJS: Double J Stent CXR: Chest X- Ray CBC: Complete Blood Count CT: Computed Tomography ATT: |
| What does NAAT stand for? | Nucleic Acid Amplification Tests-Xpert MTB/RIF/TrueNat | MUSCULOSKELETAL PLEURAL MENINGITIS LYMPHADENITIS UROGENITAL FEMALE GENITAL GASTROINTESTINAL FNA: Fine needle aspirate LJ medium: Lowenstein Jensen medium MGIT: Mycobacteria Growth Indicator tube (Liquid culture medium for mycobacteria) NAAT: Nucleic Acid Amplification Tests-Xpert MTB/RIF/TrueNat PHC: Primary health Centre TB: Tuberculosis IRL: Intermediate Reference laboratory | 242 | definition | 0.980 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | MUSCULOSKELETAL PLEURAL MENINGITIS LYMPHADENITIS UROGENITAL FEMALE GENITAL GASTROINTESTINAL FNA: Fine needle aspirate LJ medium: Lowenstein Jensen medium MGIT: Mycobacteria Growth Indicator tube (Liquid culture medium for mycobacteria) NAAT: Nucleic Acid Amplification Tests-Xpert MTB/RIF/TrueNat PHC: Primary health Centre TB: Tuberculosis IRL: Intermediate Reference laboratory | 25 | page=25,block=26 | 0.700 | valid |
| What prior exposure is particularly relevant to the symptoms described? | history of exposure to infectious TB in past 2 years | • Fever with one or more of the following › Headache › Vomiting › Seizures › Irritability/Lethargy/ Drowsiness › Loss of function e.g. recent onset deviation of eyes/mouth and/or weakness of arm/leg and/or altered mentation › Malaise, Anorexia, Weight loss • Symptoms are usually of 5 to 7 days duration with insidious onset, particularly with history of exposure to infectious TB in past 2 years Standard Treatment Workflow (STW) for the Management of | 344 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | recent onset deviation of eyes/mouth and/or weakness of arm/leg and/or altered mentation › Malaise, Anorexia, Weight loss • Symptoms are usually of 5 to 7 days duration with insidious onset, particularly with history of exposure to infectious TB in past 2 years Standard Treatment Workflow (STW) for the Management of | 12 | page=12,block=0 | 0.700 | valid |
| What should be considered if there is worsening or non-response to treatment after ruling out Crohn's disease? | possibility of Inflammatory Bowel disease | • No response to appropriate treatment • Oral drug (ATT) intolerance/cannot be given MONITORING • Assessment of response to treatment: › Clinical follow up - every month during treatment & after that every 3 months › Radiologically by USG - At the end of treatment or if worsening or non response to treatment › Microbiological - If worsening or non response to treatment • Pointers towards DR TB investigation: › Non response to treatment or Worsening or deterioration of constitutional symptoms after initial improvement. Consider possibility of Inflammatory Bowel disease after ruling out Crohn's disease • Obstructive symptoms may persist or worsen despite treatment with ATT • Monitor for › Adherence to treatment (ATT) › Adverse drug reactions- ATT induced | 533 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | Consider possibility of Inflammatory Bowel disease after ruling out Crohn's disease • Obstructive symptoms may persist or worsen despite treatment with ATT • Monitor for › Adherence to treatment (ATT) › Adverse drug reactions- ATT induced | 8 |
| What should be evaluated and addressed in all cases of TB treatment interruption? | Resons for interruption should always be evaluated & addressed in all cases (Educate & address myths/fear or any intolerance) | Interruption up to 4 weeks Resume therapy (Restart if missed within 1st 4 weeks) Reinvestigate for DRTB Rif resistance not detected Rif resistance detected Treat as MDRTB Retreat with 1st line drugs and Check for INH resistance and treat • In case interruption happens in CP & on retrieval, the patient has no clinical evidence of active disease & tests for DRTB are negative, the remaining treatment course to be completed • Resons for interruption should always be evaluated & addressed in all cases (Educate & address myths/fear or any intolerance) Interruption over 4 weeks Fibrocavitary shadows Suggestive of TB Miliary Shadows Suggestive of TB Hilar LN enlargement Suggestive of TB Paratracheal LN Suggestive of TB Pleural Effusion Pleural fluid for NAAT, cytology, biochemistry & Sputum/GA/IS for NAAT for MTB Microbiologically confirmed TB case Straw colored, exudative effusion MTB -ve MTB +ve MTB -ve | 426 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | Interruption up to 4 weeks Resume therapy (Restart if missed within 1st 4 weeks) Reinvestigate for DRTB Rif resistance not detected Rif resistance detected Treat as MDRTB Retreat with 1st line drugs and Check for INH resistance and treat • In case interruption happens in CP & on retrieval, the patient has no clinical evidence of active disease & tests for DRTB are negative, the remaining treatment course to be completed • Resons for interruption should always be evaluated & addressed in all cases (Educate & address myths/fear or any intolerance) Interruption over 4 weeks Fibrocavitary shadows |
| What does the Ministry of Health and Family Welfare aim to improve among doctors in peripheral healthcare? | implementation of the National TB Elimination Programme guide lines | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT | 507 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT |
| What is one of the goals for achieving TB elimination in India? | increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT | 198 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. |
| What is one of the goals of the Ministry of Health and Family Welfare to achieve TB elimination? | increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT | 198 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. |
| What is the purpose of formulating comprehensive algorithms for TB detection and management? | for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system | Ministry of Health and Family Welfare, Government of India To empower the primary, secondary and tertiary care physicians/surgeons of all specialties towards achieving the goal of TB elimination by increasing detection of Paediatric TB and Extrapulmonary TB with disease management protocols and pre-defined referral mechanisms. • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT | 369 | summary | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1733131854_icmr_stw_ptb_eptb.pdf | • To formulate comprehensive algorithms for detection and management of Paediatric and Extrapulmonary TB at primary, secondary and tertiary level health care system • To improve implementation of the National TB Elimination Programme guide lines by doctors working in peripheral health care and also guide the National Programme to put resources optimally for the management of these conditions Graphic Designers DESIGN TEAM EDITORIAL BOARD ICMR STW TEAM ICMR TB UNIT |