| What are glomerular diseases? | inflammatory or other disorders of the kidney’s filtering units (glomeruli) causing proteinuria, hematuria, or edema | Glomerular diseases are inflammatory or other disorders of the kidney’s filtering units (glomeruli) causing proteinuria, hematuria, or edema, and presenting as nephrotic syndrome, nephritic syndrome, RPGN, urinary abnormalities, AKI, or CKD. | 24 | definition | 0.980 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Glomerular diseases are inflammatory or other disorders of the kidney’s filtering units (glomeruli) causing proteinuria, hematuria, or edema, and presenting as nephrotic syndrome, nephritic syndrome, RPGN, urinary abnormalities, AKI, or CKD. | 1 | page=1,block=17 | 0.700 | valid |
| What do the abbreviations C3 and C4 represent? | Complement C3 and C4 | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 418 | definition | 0.940 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation ACR stand for? | Albumin-to-Creatinine Ratio | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 286 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation AKI refer to? | Acute Kidney Injury | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 319 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation ANA mean? | Antinuclear Antibody | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 344 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation CKD stand for? | Chronic Kidney Disease | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 444 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation dsDNA refer to? | Double-Stranded DNA | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 474 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What does the abbreviation eGFR mean? | Estimated Glomerular Filtration Rate | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 500 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What is the full form of ACEi? | Angiotensin-Converting Enzyme Inhibitor | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental Glomerulosclerosis HSP: Henoch-Schonlein Purpura MCD: Minimal Change Disease NSAIDs: Non-Steroidal Anti-Inflammatory Drugs RPGN: Rapidly Progressive Glomerulonephritis SPEP: Serum Protein Electrophoresis | 371 | definition | 0.900 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Infection Prevention Monitor regularly • BP & weight - each visit • Urine Examination - monthly • Serum creatinine and eGFR- (1–3 month) (more often in active disease) • • Monitor growth in children every 6 months Eye evaluation for posterior subcapsular cataract every 6 months • ACR: Albumin-to-Creatinine Ratio AKI: Acute Kidney Injury ANA: Antinuclear Antibody ACEi: Angiotensin-Converting Enzyme Inhibitor C3/C4: Complement C3 and C4 CKD: Chronic Kidney Disease dsDNA: Double-Stranded DNA eGFR: Estimated Glomerular Filtration Rate ESKD: End-Stage Kidney Disease FSGS: Focal Segmental |
| What are the key features of nephritic syndrome? | Cola-coloured urine, oliguria, edema, hypertension, Hematuria (± RBC casts), no or mild proteinuria | Syndrome Edema, frothy urine, hypoalbuminemia, hyperlipidemia. Proteinuria (Nephrotic Range): Adults: >3.5 g/1.73 m²/day or spot urine PCR >3 g/g Children: > 1000 mg/m2 per day or spot urine PCR >2 g/g Key Features Cola-coloured urine, oliguria, edema, hypertension, Hematuria (± RBC casts), no or mild proteinuria Rapid increase of Serum Creatinine within days to weeks. May have constitutional symptoms, e.g. pulmonary hemorrhage, fever, joint pains Isolated proteinuria or hematuria, usually detected on screening. Repeat urine microscopy, dipstick, proteinuria quantification Refer to nephrologist if abnormalities persist Nephrotic Syndrome Nephritic Syndrome Rapidly Progressive Glomerulonephritis Asymptomatic Urinary Abnormalities | 215 | list | 0.820 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1784807344_glomerulardiseases-updated.pdf | Proteinuria (Nephrotic Range): Adults: >3.5 g/1.73 m²/day or spot urine PCR >3 g/g Children: > 1000 mg/m2 per day or spot urine PCR >2 g/g Key Features Cola-coloured urine, oliguria, edema, hypertension, Hematuria (± RBC casts), no or mild proteinuria Rapid increase of Serum Creatinine within days to weeks. |