1098 extractive question-and-answer pairs built from Common Protocol Book ICMR, published by icmr.gov.in. The source is a 176-page publication. Source-evidenced topics include vector control, third edition, central insecticides board & registration committee, vector-borne diseases, insecticides, public health pesticides, disease elimination, insecticide resistance. Every answer is a verbatim span of text the source prints, and each row carries the passage it sits in, its offset in that passage, the source quote, the page and the location in the document, so any row can be checked against the original. Question types in the export: 710 factual, 116 definition, 112 list, 69 summary, 55 relationship, 31 table, 5 comparison. 357 of the 1098 pairs (32.5%) ask explanatory questions; the remaining 741 are factual or table-based questions. 97.27% of rows pass the corpus quality gate.
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import desidata
df = desidata.load("www-icmr-gov-in-03655b1e747009a3cbf5ab1ae67b0114")
df.head()First 10 of 1K+ rows
| question | answer | context | answer_start | question_type | knowledge_quality_score | source_document | source_quote | source_page | source_location | confidence | validation_status |
|---|---|---|---|---|---|---|---|---|---|---|---|
| What can be used if there are not enough wild-caught female mosquitoes for bioassays? | not available in sufficient number for bioassays, the F1 progeny of wild caught mosquitoes can be used | Twenty-five (mixed age) wild caught female mosquitoes are released into each cage and exposed to insecticide application for 60 minutes in both experiment and control houses. If wild caught females are not available in sufficient number for bioassays, the F1 progeny of wild caught mosquitoes can be used. Before insecticide spraying, the external doors and windows of the house should be closed. | 202 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | If wild caught females are not available in sufficient number for bioassays, the F1 progeny of wild caught mosquitoes can be used. | 101 | page=101,block=0 | 0.850 | valid |
| What criteria is used to determine if the candidate LN has met WHO efficacy standards? | considered to have met the WHO efficacy criteria based only on entomologi cal parameters | The net will be considered to have failed to meet WHO criteria if >20% of the nets sampled fail to meet the criteria, the study will be stopped. The candidate LN is considered to have met the WHO efficacy criteria based only on entomologi cal parameters. The data on malaria prevalence and incidence can be additional parameters not amounting to the failure of the net. | 165 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | The candidate LN is considered to have met the WHO efficacy criteria based only on entomologi cal parameters. | 88 | page=88,block=11 | 0.850 | valid |
| What forms the basis for evaluating new insecticides or formulations for the national vector-borne disease control programme? | based on robust scientific evaluations via laboratory and field trials on their bio-efficacy and effectiveness (on target and non-target organisms) | Therefore, the Indian Council of Medical Research (ICMR) and the National Centre for Vector Borne Diseases Control (NCVBDC) had taken the onus to evaluate and introduce new insecticides or formulations and insecticide-treated/incorporated materials into the national vector-borne disease control programme. The new products are based on robust scientific evaluations via laboratory and field trials on their bio-efficacy and effectiveness (on target and non-target organisms). Prof. | 328 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | The new products are based on robust scientific evaluations via laboratory and field trials on their bio-efficacy and effectiveness (on target and non-target organisms). | 6 | page=6,block=0 | 0.850 | valid |
| What is not required for the assessment of candidate second-in-class products? | not required to provide epidemiological data for their assessment | Subsequent products that demonstrate the same entomological effect as the first-in-class products are referred to as “second-in-class” products. Candidate second-in-class products are not required to provide epidemiological data for their assessment. Instead, they are assessed by the WHO Prequalification Unit (PQT) based on their safety, quality and entomological efficacy data (WHO, 2017a) (definition taken from WHO/CDS/GMP/2018.22. | 184 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | Candidate second-in-class products are not required to provide epidemiological data for their assessment. | 32 | page=32,block=15 | 0.850 | valid |
| What is the basis for determining outdoor spraying dosages? | based on dosage per hectare and indoor applications are based on dosage per cubic meter | The dosage(s) for conducting operational trials should be based on dosage(s) recommended on the manufacturer’s label or the optimum dosage(s) that caused at least 90% mortality in small-scale trials. Spraying outdoors are based on dosage per hectare and indoor applications are based on dosage per cubic meter. Before conducting the operational trial, the susceptibility status of the target vector species to the test insecticide should be verified following the WHO procedures (WHO, 2022). | 222 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | Spraying outdoors are based on dosage per hectare and indoor applications are based on dosage per cubic meter. | 97 | page=97,block=4 | 0.850 | valid |
| What is the definition of Preface Vector control? | a proven strategy for reducing transmission and controlling arthropod-borne diseases | Preface Vector control is a proven strategy for reducing transmission and controlling arthropod-borne diseases. Insecticides have proven to be an effective tool in vector control as these have significantly contributed to control and elimination of a few major vector-borne diseases in different regions worldwide. | 26 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | Preface Vector control is a proven strategy for reducing transmission and controlling arthropod-borne diseases. | 6 | page=6,block=0 | 0.850 | valid |
| What is the denominator used in calculating the survivorship rate of LLINs? | the total number of LLINs of each arm distributed to the surveyed households in the study cohort at the beginning of the study | The following indicators should be used and disaggregated by survey time (e.g., 6, 12, 24 or 36 months, or more if necessary): 1.1.3.2 Attrition rates (survivorship of nets in households) The numerator is the total number of LLINs of each arm (candidate or positive control/reference LN) present in the surveyed households (and available for sleeping under) × 100. The denominator is the total number of LLINs of each arm distributed to the surveyed households in the study cohort at the beginning of the study. Survivorship rate = (LLIN present during the survey /LLINs Distributed) × 100 Attrition is calculated as 1 minus survivorship. | 384 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | The denominator is the total number of LLINs of each arm distributed to the surveyed households in the study cohort at the beginning of the study. | 86 | page=86,block=2 | 0.850 | valid |
| What is the purpose of Phase I evaluation for ATSB formulations? | carried out in the laboratory to assess the efficacy and persistence of ATSB formulations incorporated with a candidate insecticide against laboratory reared target vector species | Phase I evaluation is carried out in the laboratory to assess the efficacy and persistence of ATSB formulations incorporated with a candidate insecticide against laboratory reared target vector species. The ATSB formulation containing 6–7 concentrations of a candidate insecticide should be prepared and evaluated. | 22 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | Phase I evaluation is carried out in the laboratory to assess the efficacy and persistence of ATSB formulations incorporated with a candidate insecticide against laboratory reared target vector species. | 129 | page=129,block=4 | 0.850 | valid |
| What type of surfaces are unsuitable for measuring non-dyed droplet sizes smaller than 10 µm? | not suitable for measuring non- dyed droplet sizes of <10 µm | The addition of tracer will make the smallest droplets visible as a distinct crater under an ultraviolet light microscope. Magnesium oxide coated surfaces are not suitable for measuring non- dyed droplet sizes of <10 µm. The craters in magnesium oxide/silicone- or Teflon-coated slides are examined under a microscope and the droplet size is measured. | 159 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | Magnesium oxide coated surfaces are not suitable for measuring non- dyed droplet sizes of <10 µm. | 94 | page=94,block=0 | 0.850 | valid |
| How are mosquitoes classified as dead during cone-bioassays? | if they are immobile or unable to stand or fly in a coordinated way | After 24 h of holding, percent mortalities are computed from the total number of alive and dead mosquitoes (mosquitoes will be classified as dead if they are immobile or unable to stand or fly in a coordinated way) in the replicates for each type of surface and recorded in the data recording form. | 146 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/custom_data/pdf/downloadable-books/Common_Protocol_Book_ICMR.pdf | After 24 h of holding, percent mortalities are computed from the total number of alive and dead mosquitoes (mosquitoes will be classified as dead if they are immobile or unable to stand or fly in a coordinated way) in the replicates for each type of surface and recorded in the data recording form. | 43 | page=43,block=5 | 0.700 | valid |
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