| What causes melioidosis? | Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 13 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. | 1 | [{"evidence_id":"B000002","location":{"page":1,"block":2,"bbox":[73.34,191.0,303.15,514.87],"column":0,"reading_order":2}}] | 1.0 | valid |
| During which season do most cases of melioidosis occur? | It is seasonal,
with 75–85% of cases occurring during the
rainy season. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 114 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | It is seasonal,
with 75–85% of cases occurring during the
rainy season. | 1 | [{"evidence_id":"B000002","location":{"page":1,"block":2,"bbox":[73.34,191.0,303.15,514.87],"column":0,"reading_order":2}}] |
| What is the clinical spectrum of melioidosis? | The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 186 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia. |
| What is the case fatality rate of melioidosis in endemic regions? | Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 323 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. | 1 |
| What are some risk factors associated with melioidosis? | Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 421 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. |
| What is the most common risk factor for melioidosis? | Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 607 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. | 1 |
| Where is melioidosis endemic? | The disease is
endemic in Southeast Asia and Northern
Australia. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 704 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | The disease is
endemic in Southeast Asia and Northern
Australia. | 1 | [{"evidence_id":"B000002","location":{"page":1,"block":2,"bbox":[73.34,191.0,303.15,514.87],"column":0,"reading_order":2}}] |
| How is melioidosis classified in terms of bioterrorism agents? | It is classified as category B
bioterrorism agent. | INTRODUCTION
Melioidosis is an infectious disease caused
by
a
Gram
negative
bacterium,
Burkholderia pseudomallei. It is seasonal,
with 75–85% of cases occurring during the
rainy season. The clinical spectrum of
illness
is
diverse
and
ranges
from
pulmonary consolidation and localized
abscesses to rapidly fatal septicemia.
Melioidosis has a high case fatality rate
(CFR) ranging from 16% to 50% in known
endemic regions. Several risk factors are
associated
with
melioidosis
including
immunosuppressive conditions such as
diabetes and other diseases like chronic
kidney
disease,
and
certain
drug
treatments. Diabetes mellitus is the most
common risk factor and increases the
relative risk of melioidosis. The disease is
endemic in Southeast Asia and Northern
Australia. It is classified as category B
bioterrorism agent. | 769 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | It is classified as category B
bioterrorism agent. | 1 | [{"evidence_id":"B000002","location":{"page":1,"block":2,"bbox":[73.34,191.0,303.15,514.87],"column":0,"reading_order":2}}] |
| Who first described melioidosis as a 'Glanders-like disease'? | Alfred Whitmore and CS Krishnaswami
first
described
melioidosis
as
a
“Glanders-like
disease”
among
morphine addicts in Rangoon in 1911. | HISTORICAL BACKGROUND
Alfred Whitmore and CS Krishnaswami
first
described
melioidosis
as
a
“Glanders-like
disease”
among
morphine addicts in Rangoon in 1911.
Stanton and Fletcher in 1932 proposed
the name “melioidosis”, derived from the
Greek melis meaning “a distemper of
asses” and suffixes -oid (similar to) and
-osis (a condition). | 22 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Alfred Whitmore and CS Krishnaswami
first
described
melioidosis
as
a
“Glanders-like
disease”
among
morphine addicts in Rangoon in 1911. | 1 | [{"evidence_id":"B000006","location":{"page":1,"block":6,"bbox":[310.61,191.0,549.11,336.65],"column":2,"reading_order":6}}] | 1.0 | valid |
| Who proposed the name 'melioidosis'? | Stanton and Fletcher in 1932 proposed
the name “melioidosis” | HISTORICAL BACKGROUND
Alfred Whitmore and CS Krishnaswami
first
described
melioidosis
as
a
“Glanders-like
disease”
among
morphine addicts in Rangoon in 1911.
Stanton and Fletcher in 1932 proposed
the name “melioidosis”, derived from the
Greek melis meaning “a distemper of
asses” and suffixes -oid (similar to) and
-osis (a condition). | 158 | factual | 1.0 | https://ncdc.mohfw.gov.in/uploads/glimpse_pdfs/1770282109_meliodosis-cd_alert-duly-launched-by-hon_ble-hfm-on-annual-day-on-30th-july-2019.pdf | Stanton and Fletcher in 1932 proposed
the name “melioidosis” | 1 | [{"evidence_id":"B000006","location":{"page":1,"block":6,"bbox":[310.61,191.0,549.11,336.65],"column":2,"reading_order":6}}] | 1.0 | valid |