| What abdominal feature might indicate a partially obstructed dilated bowel loop? | a moving mass -"gola" formation | • Anthropometry • General physical & systemic examination • Look for peripheral LAP, ascites, hepatosplenomegaly, doughy feel of abdomen, palpable abdominal lump, visible peristalsis or a moving mass -"gola" formation due to partially obstructed dilated bowel loop • One or more of following › Recurrent/chronic abdominal pain in presence of red flag signs › Abdominal distension/mass › Altered bowel habits • Constitutional symptoms like Presence of Fever >2 weeks, Anorexia, Unexplained weight loss or no weight gain in last 3 months despite adequate nutrition may be present • History of contact with TB patient may also be present • Recurrent intestinal colic • Altered bowel habits • Chronic diarrhoea • Partial/complete intestinal obstruction • Weight loss, anorexia • Palpable abdominal lump • Lower gastrointestinal bleeding • Abdominal pain • Fever • Jaundice • Weight loss • Anorexia • Hepatomegaly • Splenomegaly • Hepatic abscess • Palpable abdominal lump • Abnormal LFTs WHEN TO SUSPECT? | 186 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | • Anthropometry • General physical & systemic examination • Look for peripheral LAP, ascites, hepatosplenomegaly, doughy feel of abdomen, palpable abdominal lump, visible peristalsis or a moving mass -"gola" formation due to partially obstructed dilated bowel loop • One or more of following › Recurrent/chronic abdominal pain in presence of red flag signs › Abdominal distension/mass › Altered bowel habits • Constitutional symptoms like Presence of Fever >2 weeks, Anorexia, Unexplained weight loss or no weight gain in last 3 months despite adequate nutrition may be present • History of contact | 8 | page=8,block=27 | 0.700 | valid |
| What does the abbreviation CBNAAT stand for in tuberculosis diagnostics? | Cartidge-based Nucleic Acid Amplification test | Km, Cm, Lzd) **LPA may be done directly if smear +ve else send for MGIT followed by FLPA to evaluate for H (inhA and/ or KatG mutn) and Eto (inhA) resistance ADA: Adenosine Deaminase BAL: Broncho-alveolar lavage CBNAAT: Cartidge-based Nucleic Acid Amplification test CECT: Contrast enhanced CT CP: Continuation phase CT: Computed tomography DRTB: Drug resistant TB DST: Drug sensitivity test EPTB: Extra-pulmonary TB ETO: Ethionamide FDC: Fixed dose combination FL-LPA: First line - Line probe assay FQ: Fluoroquinolones GA: Gastric aspirate H: Isoniazid HIV: Human Immunodeficiency virus HRZE: Isoniazid; Rifampicin; Pyrazinamide; Ethambutol IGRA: Interferon Gamma Release assay IS: Induced sputum LN: Lymph node MAC: Mid Arm Circumference MTB: Mycobacterium Tuberculosis NAAT: Nucleic acid amplification test PPD: Purified Protein Derivative RIF: Rifampicin SAM: Severe acute malnutrition SLI: Second line injectables SL-LPA: Second line - Line probe assay TST: Tuberculin skin test USG: Ultrasonography ZN: Ziehl Neelson | 220 | definition | 1.000 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | Km, Cm, Lzd) **LPA may be done directly if smear +ve else send for MGIT followed by FLPA to evaluate for H (inhA and/ or KatG mutn) and Eto (inhA) resistance ADA: Adenosine Deaminase BAL: Broncho-alveolar lavage CBNAAT: Cartidge-based Nucleic Acid Amplification test CECT: Contrast enhanced CT CP: Continuation phase CT: Computed tomography DRTB: Drug resistant TB DST: Drug sensitivity test EPTB: Extra-pulmonary TB ETO: Ethionamide FDC: Fixed dose combination FL-LPA: First line - Line probe assay FQ: Fluoroquinolones GA: Gastric aspirate H: Isoniazid HIV: Human Immunodeficiency virus HRZE: |
| What makes tuberculosis unlikely in the context of lymph node size and symptoms? | the lymphnodes are small (< 2 cm) AND are persisting for a long time (months to years) without any systemic symptoms | Mtb or AFB detected Choose appropriate regiment for DSTB vs DRTB based on NAAT result If chest x-ray abnormal: Get Sputum /Induced sputum/GA for NAAT and AFB TB is unlikely if: the lymphnodes are small (< 2 cm) AND are persisting for a long time (months to years) without any systemic symptoms Peripheral Lymph node > 2cm in one or more sites | 177 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | Mtb or AFB detected Choose appropriate regiment for DSTB vs DRTB based on NAAT result If chest x-ray abnormal: Get Sputum /Induced sputum/GA for NAAT and AFB TB is unlikely if: the lymphnodes are small (< 2 cm) AND are persisting for a long time (months to years) without any systemic symptoms Peripheral Lymph node > 2cm in one or more sites | 10 | page=10,block=11 | 0.700 | valid |
| What might a doughy feel of the abdomen indicate? | partially obstructed dilated bowel loop | • Anthropometry • General physical & systemic examination • Look for peripheral LAP, ascites, hepatosplenomegaly, doughy feel of abdomen, palpable abdominal lump, visible peristalsis or a moving mass -"gola" formation due to partially obstructed dilated bowel loop • One or more of following › Recurrent/chronic abdominal pain in presence of red flag signs › Abdominal distension/mass › Altered bowel habits • Constitutional symptoms like Presence of Fever >2 weeks, Anorexia, Unexplained weight loss or no weight gain in last 3 months despite adequate nutrition may be present • History of contact with TB patient may also be present • Recurrent intestinal colic • Altered bowel habits • Chronic diarrhoea • Partial/complete intestinal obstruction • Weight loss, anorexia • Palpable abdominal lump • Lower gastrointestinal bleeding • Abdominal pain • Fever • Jaundice • Weight loss • Anorexia • Hepatomegaly • Splenomegaly • Hepatic abscess • Palpable abdominal lump • Abnormal LFTs WHEN TO SUSPECT? | 225 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | • Anthropometry • General physical & systemic examination • Look for peripheral LAP, ascites, hepatosplenomegaly, doughy feel of abdomen, palpable abdominal lump, visible peristalsis or a moving mass -"gola" formation due to partially obstructed dilated bowel loop • One or more of following › Recurrent/chronic abdominal pain in presence of red flag signs › Abdominal distension/mass › Altered bowel habits • Constitutional symptoms like Presence of Fever >2 weeks, Anorexia, Unexplained weight loss or no weight gain in last 3 months despite adequate nutrition may be present • History of contact |
| What past exposure is commonly linked to symptoms of TB with insidious onset? | history of exposure to infectious TB in past 2 years | • Fever with one or more of the following › Headache › Vomiting › Seizures › Irritability/Lethargy/ Drowsiness › Loss of function e.g. recent onset deviation of eyes/mouth and/or weakness of arm/leg and/or altered mentation › Malaise, Anorexia, Weight loss • Symptoms are usually of 5 to 7 days duration with insidious onset, particularly with history of exposure to infectious TB in past 2 years Standard Treatment Workflow (STW) for the Management of | 344 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | recent onset deviation of eyes/mouth and/or weakness of arm/leg and/or altered mentation › Malaise, Anorexia, Weight loss • Symptoms are usually of 5 to 7 days duration with insidious onset, particularly with history of exposure to infectious TB in past 2 years Standard Treatment Workflow (STW) for the Management of | 12 | page=12,block=0 | 0.700 | valid |
| Which institution does Dr Jagdish Prasad Goyal represent? | All India Institute of Medical Sciences, Jodhpur | • Prof. Sushil Kumar Kabra, Professor, Paediatrics, All India Institute of Medical Sciences, New Delhi CO-CHAIR • Dr Varinder Singh, Director Professor, Paediatrics, Lady Hardinge Medical College, New Delhi MEMBERS* • Dr Amber Kumar, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bhopal • Dr Jagdish Prasad Goyal, Professor, Paediatrics, All India Institute of Medical Sciences, Jodhpur • Dr Joseph L Mathew, Professor, Paediatrics Pulmonology, Postgraduate Institute of Medical Education and Research, Chandigarh • Dr Kana Ram Jat, Additional Professor, Paediatrics, All India Institute of Medical Sciences. | 367 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | Sushil Kumar Kabra, Professor, Paediatrics, All India Institute of Medical Sciences, New Delhi CO-CHAIR • Dr Varinder Singh, Director Professor, Paediatrics, Lady Hardinge Medical College, New Delhi MEMBERS* • Dr Amber Kumar, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bhopal • Dr Jagdish Prasad Goyal, Professor, Paediatrics, All India Institute of Medical Sciences, Jodhpur • Dr Joseph L Mathew, Professor, Paediatrics Pulmonology, Postgraduate Institute of Medical Education and Research, Chandigarh • Dr Kana Ram Jat, Additional Professor, Paediatrics, All India |
| Which institution does Dr Krishna Mohan Gulla work for? | All India Institute of Medical Sciences, Bhubaneswar | New Delhi • Dr Krishna Mohan Gulla, Associate Professor, Paediatrics, All India Institute of Medical Sciences, Bhubaneswar • Dr Manjula Datta, Chief Scientist, ASPIRE Chennai • Dr Samriti Gupta, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bilaspur • Dr Sangeeta Sharma, Professor, Paediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi | 70 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | New Delhi • Dr Krishna Mohan Gulla, Associate Professor, Paediatrics, All India Institute of Medical Sciences, Bhubaneswar • Dr Manjula Datta, Chief Scientist, ASPIRE Chennai • Dr Samriti Gupta, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bilaspur • Dr Sangeeta Sharma, Professor, Paediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi | 13 | page=13,block=3 | 0.700 | valid |
| Which institution is Dr Sangeeta Sharma associated with? | National Institute of Tuberculosis and Respiratory Diseases, New Delhi | New Delhi • Dr Krishna Mohan Gulla, Associate Professor, Paediatrics, All India Institute of Medical Sciences, Bhubaneswar • Dr Manjula Datta, Chief Scientist, ASPIRE Chennai • Dr Samriti Gupta, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bilaspur • Dr Sangeeta Sharma, Professor, Paediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi | 325 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | New Delhi • Dr Krishna Mohan Gulla, Associate Professor, Paediatrics, All India Institute of Medical Sciences, Bhubaneswar • Dr Manjula Datta, Chief Scientist, ASPIRE Chennai • Dr Samriti Gupta, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bilaspur • Dr Sangeeta Sharma, Professor, Paediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi | 13 | page=13,block=3 | 0.700 | valid |
| Which institution is Prof. Sushil Kumar Kabra associated with? | All India Institute of Medical Sciences, New Delhi | • Prof. Sushil Kumar Kabra, Professor, Paediatrics, All India Institute of Medical Sciences, New Delhi CO-CHAIR • Dr Varinder Singh, Director Professor, Paediatrics, Lady Hardinge Medical College, New Delhi MEMBERS* • Dr Amber Kumar, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bhopal • Dr Jagdish Prasad Goyal, Professor, Paediatrics, All India Institute of Medical Sciences, Jodhpur • Dr Joseph L Mathew, Professor, Paediatrics Pulmonology, Postgraduate Institute of Medical Education and Research, Chandigarh • Dr Kana Ram Jat, Additional Professor, Paediatrics, All India Institute of Medical Sciences. | 52 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | Sushil Kumar Kabra, Professor, Paediatrics, All India Institute of Medical Sciences, New Delhi CO-CHAIR • Dr Varinder Singh, Director Professor, Paediatrics, Lady Hardinge Medical College, New Delhi MEMBERS* • Dr Amber Kumar, Assistant Professor, Paediatrics, All India Institute of Medical Sciences, Bhopal • Dr Jagdish Prasad Goyal, Professor, Paediatrics, All India Institute of Medical Sciences, Jodhpur • Dr Joseph L Mathew, Professor, Paediatrics Pulmonology, Postgraduate Institute of Medical Education and Research, Chandigarh • Dr Kana Ram Jat, Additional Professor, Paediatrics, All India |
| Which unit does Dr A M Khan belong to at ICMR? | Epidemiology and Communicable Diseases- TB Unit | Prof. Dr Balram Bhargava, Secretary, DHR & Director General, ICMR Dr Samiran Panda, Additional Director General, ICMR ICMR COORDINATING UNIT Epidemiology and Communicable Diseases- TB Unit Dr A M Khan Scientist G, ICMR, New Delhi Dr Manjula Singh, Scientist F, ICMR, New Delhi. Dr Sudipto Pallab Roy, Scientist E, ICMR, New Delhi Ms Saumya Deol, Scientist B, ICMR, New Delhi Dr Sneh Shalini, Technical Officer B, ICMR, New Delhi | 141 | relationship | 0.970 | https://www.icmr.gov.in/icmrobject/uploads/STWs/1725964681_paediatric_tuberculosis_all.pdf | Dr Balram Bhargava, Secretary, DHR & Director General, ICMR Dr Samiran Panda, Additional Director General, ICMR ICMR COORDINATING UNIT Epidemiology and Communicable Diseases- TB Unit Dr A M Khan Scientist G, ICMR, New Delhi Dr Manjula Singh, Scientist F, ICMR, New Delhi. | 15 | page=15,block=2 | 0.700 | valid |